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Cancerous cells secrete α-N-acetylgalactosaminidase (NaGalase) into the blood stream, resulting in deglycosylation of serum vitamin D3-binding protein (known as Gc protein), which is a precursor for macrophage initiating aspect (MAF). Incubation of Gc protein with incapacitated β-galactosidase and sialidase produces the most powerful macrophage activating element (designated GcMAF). Administratio

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